| Assay ID | Title | Year | Journal | Article |
|---|
| AID440420 | Inhibition of autoactivated human pro-MMP12 after 4 hrs by fluorimetry | 2009 | Journal of medicinal chemistry, Oct-22, Volume: 52, Issue:20
| Design, synthesis, biological evaluation, and NMR studies of a new series of arylsulfones as selective and potent matrix metalloproteinase-12 inhibitors. |
| AID1271564 | Inhibition of Bacillus thermoproteolyticus thermolysin pretreated with compound for 1 hr followed by the addition of 3.33 uM bradykinin like substrate by spectrofluorometry assay | 2016 | European journal of medicinal chemistry, Jan-27, Volume: 108 | Synthesis, experimental evaluation and molecular modelling of hydroxamate derivatives as zinc metalloproteinase inhibitors. |
| AID242990 | Relative binding affinity for MMP2 and MMP9 as ratio of IC50 | 2005 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 15, Issue:5
| N-i-Propoxy-N-biphenylsulfonylaminobutylhydroxamic acids as potent and selective inhibitors of MMP-2 and MT1-MMP. |
| AID242986 | Relative binding affinity for MMP2 and MMP1 as ratio of IC50 | 2005 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 15, Issue:5
| N-i-Propoxy-N-biphenylsulfonylaminobutylhydroxamic acids as potent and selective inhibitors of MMP-2 and MT1-MMP. |
| AID241641 | Inhibition of human matrix metalloprotease-7 | 2005 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 15, Issue:5
| N-i-Propoxy-N-biphenylsulfonylaminobutylhydroxamic acids as potent and selective inhibitors of MMP-2 and MT1-MMP. |
| AID440426 | Inhibition of para-aminophenylmercuric acetate-activated human pro-MMP13 after 4 hrs by fluorimetry | 2009 | Journal of medicinal chemistry, Oct-22, Volume: 52, Issue:20
| Design, synthesis, biological evaluation, and NMR studies of a new series of arylsulfones as selective and potent matrix metalloproteinase-12 inhibitors. |
| AID440425 | Inhibition of para-aminophenylmercuric acetate-activated human pro-MMP1 after 4 hrs by fluorimetry | 2009 | Journal of medicinal chemistry, Oct-22, Volume: 52, Issue:20
| Design, synthesis, biological evaluation, and NMR studies of a new series of arylsulfones as selective and potent matrix metalloproteinase-12 inhibitors. |
| AID241643 | Inhibition of human matrix metalloprotease-9 | 2005 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 15, Issue:5
| N-i-Propoxy-N-biphenylsulfonylaminobutylhydroxamic acids as potent and selective inhibitors of MMP-2 and MT1-MMP. |
| AID241639 | Inhibition of human matrix metalloprotease-2 | 2005 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 15, Issue:5
| N-i-Propoxy-N-biphenylsulfonylaminobutylhydroxamic acids as potent and selective inhibitors of MMP-2 and MT1-MMP. |
| AID440428 | Inhibition of human recombinant pro-MMP16 catalytic domain after 4 hrs by fluorimetry | 2009 | Journal of medicinal chemistry, Oct-22, Volume: 52, Issue:20
| Design, synthesis, biological evaluation, and NMR studies of a new series of arylsulfones as selective and potent matrix metalloproteinase-12 inhibitors. |
| AID241640 | Inhibition of human matrix metalloprotease-3 | 2005 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 15, Issue:5
| N-i-Propoxy-N-biphenylsulfonylaminobutylhydroxamic acids as potent and selective inhibitors of MMP-2 and MT1-MMP. |
| AID1271559 | Inhibition of recombinant human MMP9 after 2 hrs using FS-6 as substrate by fluorometry | 2016 | European journal of medicinal chemistry, Jan-27, Volume: 108 | Synthesis, experimental evaluation and molecular modelling of hydroxamate derivatives as zinc metalloproteinase inhibitors. |
| AID440424 | Inhibition of para-aminophenylmercuric acetate-activated human recombinant pro-MMP2 catalytic domain after 4 hrs by fluorimetry | 2009 | Journal of medicinal chemistry, Oct-22, Volume: 52, Issue:20
| Design, synthesis, biological evaluation, and NMR studies of a new series of arylsulfones as selective and potent matrix metalloproteinase-12 inhibitors. |
| AID1271560 | Inhibition of recombinant human MMP2 after 2 hrs using FS-6 as substrate by fluorometry | 2016 | European journal of medicinal chemistry, Jan-27, Volume: 108 | Synthesis, experimental evaluation and molecular modelling of hydroxamate derivatives as zinc metalloproteinase inhibitors. |
| AID242994 | Relative binding affinity for MMP2 and MMP-3 as ratio of IC50 | 2005 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 15, Issue:5
| N-i-Propoxy-N-biphenylsulfonylaminobutylhydroxamic acids as potent and selective inhibitors of MMP-2 and MT1-MMP. |
| AID241672 | Inhibition of human matrix metalloprotease-14 | 2005 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 15, Issue:5
| N-i-Propoxy-N-biphenylsulfonylaminobutylhydroxamic acids as potent and selective inhibitors of MMP-2 and MT1-MMP. |
| AID440422 | Inhibition of para-aminophenylmercuric acetate-activated human pro-MMP8 after 4 hrs by fluorimetry | 2009 | Journal of medicinal chemistry, Oct-22, Volume: 52, Issue:20
| Design, synthesis, biological evaluation, and NMR studies of a new series of arylsulfones as selective and potent matrix metalloproteinase-12 inhibitors. |
| AID1271561 | Inhibition of Bacillus thermoproteolyticus pseudolysin pretreated with compound for 15 mins followed by the addition of Abz-Ala-Gly-leu-Ala-p-nitrobenzalamide as substrate by spectrofluorometry | 2016 | European journal of medicinal chemistry, Jan-27, Volume: 108 | Synthesis, experimental evaluation and molecular modelling of hydroxamate derivatives as zinc metalloproteinase inhibitors. |
| AID241642 | Inhibition of human matrix metalloprotease-8 | 2005 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 15, Issue:5
| N-i-Propoxy-N-biphenylsulfonylaminobutylhydroxamic acids as potent and selective inhibitors of MMP-2 and MT1-MMP. |
| AID440421 | Inhibition of para-aminophenylmercuric acetate-activated human recombinant pro-MMP9 catalytic domain after 4 hrs by fluorimetry | 2009 | Journal of medicinal chemistry, Oct-22, Volume: 52, Issue:20
| Design, synthesis, biological evaluation, and NMR studies of a new series of arylsulfones as selective and potent matrix metalloproteinase-12 inhibitors. |
| AID242989 | Relative binding affinity for MMP2 and MMP8 as ratio of IC50 | 2005 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 15, Issue:5
| N-i-Propoxy-N-biphenylsulfonylaminobutylhydroxamic acids as potent and selective inhibitors of MMP-2 and MT1-MMP. |
| AID440423 | Inhibition of trypsin activated human pro-MMP3 after 4 hrs by fluorimetry | 2009 | Journal of medicinal chemistry, Oct-22, Volume: 52, Issue:20
| Design, synthesis, biological evaluation, and NMR studies of a new series of arylsulfones as selective and potent matrix metalloproteinase-12 inhibitors. |
| AID1271563 | Inhibition of Bacillus thermoproteolyticus thermolysin pretreated with compound for 15 mins followed by the addition of 75 uM Abz-Ala-Gly-leu-Ala-p-nitrobenzalamide as substrate by spectrofluorometry | 2016 | European journal of medicinal chemistry, Jan-27, Volume: 108 | Synthesis, experimental evaluation and molecular modelling of hydroxamate derivatives as zinc metalloproteinase inhibitors. |
| AID440427 | Inhibition of human recombinant pro-MMP14 catalytic domain after 4 hrs by fluorimetry | 2009 | Journal of medicinal chemistry, Oct-22, Volume: 52, Issue:20
| Design, synthesis, biological evaluation, and NMR studies of a new series of arylsulfones as selective and potent matrix metalloproteinase-12 inhibitors. |
| AID1271562 | Inhibition of Pseudomonas aeruginosa pseudolysin pretreated with compound for 1 hr followed by the addition of 1.73 uM bradykinin like substrate by spectrofluorometry | 2016 | European journal of medicinal chemistry, Jan-27, Volume: 108 | Synthesis, experimental evaluation and molecular modelling of hydroxamate derivatives as zinc metalloproteinase inhibitors. |
| AID1271565 | Inhibition of recombinant human ADAM17 after 30 mins using FS-6 as substrate by fluorometry | 2016 | European journal of medicinal chemistry, Jan-27, Volume: 108 | Synthesis, experimental evaluation and molecular modelling of hydroxamate derivatives as zinc metalloproteinase inhibitors. |
| AID241638 | Inhibition of human matrix metalloprotease-1 | 2005 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 15, Issue:5
| N-i-Propoxy-N-biphenylsulfonylaminobutylhydroxamic acids as potent and selective inhibitors of MMP-2 and MT1-MMP. |
| AID1246489 | Antiinvasive activity in human U87MG cells after 24 hrs by Transwell matrigel assay | 2015 | Journal of medicinal chemistry, Sep-24, Volume: 58, Issue:18
| N-O-Isopropyl Sulfonamido-Based Hydroxamates as Matrix Metalloproteinase Inhibitors: Hit Selection and in Vivo Antiangiogenic Activity. |
| AID1508630 | Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident proteome: Secreted ER Calcium Modulated Protein (SERCaMP) assay | 2021 | Cell reports, 04-27, Volume: 35, Issue:4
| A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. |
| AID1347082 | qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: LASV Primary Screen - GLuc reporter signal | 2020 | Antiviral research, 01, Volume: 173 | A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity. |
| AID1347086 | qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lymphocytic Choriomeningitis Arenaviruses (LCMV): LCMV Primary Screen - GLuc reporter signal | 2020 | Antiviral research, 01, Volume: 173 | A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity. |
| AID1347050 | Natriuretic polypeptide receptor (hNpr2) antagonism - Pilot subtype selectivity assay | 2019 | Science translational medicine, 07-10, Volume: 11, Issue:500
| Inhibition of natriuretic peptide receptor 1 reduces itch in mice. |
| AID504812 | Inverse Agonists of the Thyroid Stimulating Hormone Receptor: HTS campaign | 2010 | Endocrinology, Jul, Volume: 151, Issue:7
| A small molecule inverse agonist for the human thyroid-stimulating hormone receptor. |
| AID1347045 | Natriuretic polypeptide receptor (hNpr1) antagonism - Pilot counterscreen GloSensor control cell line | 2019 | Science translational medicine, 07-10, Volume: 11, Issue:500
| Inhibition of natriuretic peptide receptor 1 reduces itch in mice. |
| AID588349 | qHTS for Inhibitors of ATXN expression: Validation of Cytotoxic Assay | | | |
| AID1347083 | qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: Viability assay - alamar blue signal for LASV Primary Screen | 2020 | Antiviral research, 01, Volume: 173 | A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity. |
| AID588378 | qHTS for Inhibitors of ATXN expression: Validation | | | |
| AID504810 | Antagonists of the Thyroid Stimulating Hormone Receptor: HTS campaign | 2010 | Endocrinology, Jul, Volume: 151, Issue:7
| A small molecule inverse agonist for the human thyroid-stimulating hormone receptor. |
| AID504836 | Inducers of the Endoplasmic Reticulum Stress Response (ERSR) in human glioma: Validation | 2002 | The Journal of biological chemistry, Apr-19, Volume: 277, Issue:16
| Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells. |
| AID1347049 | Natriuretic polypeptide receptor (hNpr1) antagonism - Pilot screen | 2019 | Science translational medicine, 07-10, Volume: 11, Issue:500
| Inhibition of natriuretic peptide receptor 1 reduces itch in mice. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |